Advances in periodontal care continue to focus on one key goal: helping the body heal as effectively and predictably as possible after treatment. Modern techniques now allow periodontists to work with the body’s own biology rather than relying solely on external materials.
One of the newest developments available at Pure Periodontics in the City of London is ENDORET® (PRGF®), a regenerative technique that uses a patient’s own healing factors to support recovery after periodontal procedures.
Under the clinical leadership of Dr Neesha Patel, Clinical Director at Pure Periodontics and former Consultant Periodontist at King’s College Hospital, the practice regularly adopts evidence based innovations that aim to improve both clinical outcomes and the patient experience.
This article explains what ENDORET® (PRGF®) is, how it works, and when it may be used as part of modern periodontal care.
What is ENDORET® (PRGF®)?
ENDORET® (PRGF®) stands for Plasma Rich in Growth Factors. It is a regenerative technology that uses a small sample of a patient’s own blood to produce a concentrated solution containing proteins that play an important role in natural healing.
The process is straightforward and similar to a routine blood test.
A small blood sample is taken from the patient’s arm. The sample is then processed in a sterile system that separates and concentrates the part of the blood that contains platelets and growth factors. These natural proteins are known to be involved in tissue repair and regeneration.
Once prepared, the PRGF can be applied to the surgical area during periodontal treatment. Depending on the procedure, it may be used in liquid form, as a gel, or as a thin fibrin membrane that sits over the treated area.
Because the material comes from the patient’s own body, it is described as 100% autologous. This means there is very little risk of allergic reaction or rejection.
Why healing matters in periodontal treatment
Periodontal procedures are designed to treat gum disease, stabilise the supporting structures of the teeth and in some cases regenerate lost tissue.
While modern periodontal techniques are highly effective, the healing phase remains an important part of successful treatment. The way tissues recover in the early days and weeks following a procedure can influence the final outcome.
For this reason, periodontists increasingly look for ways to support the body’s natural repair processes. Techniques such as PRGF are designed to create an environment that encourages stable wound healing and soft tissue recovery.
At practices such as Pure Periodontics, the aim is not only to treat gum disease but also to optimise healing conditions wherever possible.
How PRGF may support recovery
Platelets contain growth factors that are naturally released during injury and tissue repair. These proteins signal the body to begin the healing process and help coordinate the activity of cells involved in tissue regeneration.
By concentrating these factors and applying them directly to the treatment site, PRGF aims to enhance this natural response.
In selected periodontal cases, clinicians may use PRGF with the intention of supporting:
- Early wound stability
- Soft tissue healing
- Reduced swelling during early recovery
- Reduced discomfort for some patients
- Improved predictability of healing in certain procedures
It is important to note that outcomes vary between individuals. PRGF supports the body’s own healing mechanisms but cannot guarantee a particular result.
Good oral hygiene, professional follow up and careful post operative care remain essential parts of successful periodontal treatment.
When PRGF may be used in periodontal procedures
ENDORET® (PRGF®) can be incorporated into a range of periodontal treatments.
A periodontist may recommend it during procedures such as:
- Periodontal flap procedures, where the gums are gently lifted to allow deep cleaning and treatment of the root surfaces
- Periodontal regenerative procedures, where the aim is to rebuild structures lost through gum disease
- Soft tissue procedures, where supporting healing of the gums is particularly important
In some cases, PRGF may allow a more conservative approach by supporting the body’s healing response without the need for additional materials.
In other situations, it may be used alongside established regenerative techniques to achieve the most predictable long term result.
The decision is always made on a case by case basis after a full periodontal assessment.
What happens on the day of treatment
For patients receiving PRGF as part of their periodontal care, the process is usually completed within the same appointment.
The steps typically include:
Blood sample
A small amount of blood is taken from the patient’s arm, similar to a routine blood test.
Preparation
The blood is placed into a specialised centrifuge that separates and concentrates the growth factor rich component.
Application during treatment
Once prepared, the PRGF is applied directly to the treatment site in the most appropriate format for the procedure.
Aftercare
Patients follow the same post operative instructions normally given after periodontal procedures. PRGF is designed to support healing but it does not replace good aftercare.
Safety and suitability
Because PRGF uses the patient’s own biological material, the risk of allergic reaction is extremely low. The technique has been used in various areas of medicine and dentistry where tissue healing is important.
However, as with any clinical procedure, there are factors that the treating clinician must consider.
Patients should inform their periodontist if they:
- Tend to faint during blood tests
- Have a bleeding or platelet disorder
- Take blood thinning medication
- Have medical conditions that affect healing such as poorly controlled diabetes
- Smoke or vape
Smoking and vaping in particular can significantly affect gum healing and the long term success of periodontal treatment.
There may also be temporary bruising or soreness at the blood draw site and the procedure can add a small amount of additional chair time during the appointment.
A biological approach to periodontal care
Regenerative techniques such as ENDORET® (PRGF®) reflect a broader shift in dentistry towards biologically driven treatments. Rather than simply repairing damage, clinicians aim to work with the body’s own processes to encourage healthy tissue recovery.
Dr Neesha Patel has extensive experience in advanced periodontal procedures and continues to incorporate evidence based technologies that support predictable outcomes for patients.
At Pure Periodontics, every treatment plan is tailored to the individual. PRGF may be recommended in some cases, while in others more traditional approaches remain the most appropriate option.
The goal is always the same: to treat gum disease effectively while supporting the best possible healing environment.
The importance of ongoing care
While innovations such as PRGF can support the healing process, the long term health of the gums still depends on daily plaque control and regular periodontal maintenance.
Gum disease is a chronic condition that requires ongoing management. Professional care combined with excellent home oral hygiene remains the most reliable way to protect the supporting structures of the teeth.
Patients considering periodontal treatment are encouraged to discuss all available options with their periodontist so they can make an informed decision about their care.
Pure Periodontics is a specialist periodontal practice in the City of London led by Dr Neesha Patel, Clinical Director and former Consultant Periodontist at King’s College Hospital. The practice provides advanced diagnosis and treatment of gum disease, including regenerative and surgical periodontal therapies designed to support long term oral health.